2-Deoxy D-Glucose in COVID-19: Current Research Trends

2-Deoxy D- glucose is a novel drug. It an analogue of which has innate therapeutic uses due to both its antiviral properties as well anti-neoplastic action. The SARS-CoV-2 virus binds the host cell via (S2) spike glycoprotein. Once viral entry been gained into hijacks host’s intracellular machinery 2 factors; 3CLproand NSP15. shown through use Toxicity estimation software Molinspiration that and aforementioned isomers can effectively bind with 3CLpro NSP15 intern thus immobilize incapacitation receptors. On molecular level derivatives produce H bond glutamine AA residues spike, form Hydrogen Deoxy D-glucose proline protease. evident in silico studies have ability offer further protection or imperative diminution capabilities treatment patients COVID-19 infection. promising results clinical trials produced faster recovery hospitalized abridged additional oxygen dependence various states across India. scope potential for evident. therefore great importance vivo are conducted order expedite process bringing this potentially lifesaving drug market.